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Correction method for quantitative area determination of overlapping chromatographic peaks based on the exponentially modified Gaussian (EMG) model

✍ Scribed by Binsheng, Lin ;Peichang, Lu


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
346 KB
Volume
10
Category
Article
ISSN
0935-6304

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✦ Synopsis


A simple method is presented for peak area correction of overlapping peaks. This correction is necessary for the normal approach of dealing with overlapping peaks by a vertical line at the valley point. The relative area errors caused by this vertical line are calculated as the correction factors in three dimensions of peak separation, peak ratio, and peak tailing skew. The calculation is based on the exponentially modified Gaussian asymmetric peak model.