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Corpus callosotomy for the treatment of intractable epilepsy

✍ Scribed by Anthony M. Murro; Herman F. Flanigin; Brian B. Gallagher; Don W. King; Joseph R. Smith

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
727 KB
Volume
2
Category
Article
ISSN
0920-1211

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✦ Synopsis

Twenty-five patients underwent anterior corpus callosotomy (ACC) for treatment of uncontrolled seizures. Two patients died, and 6 patients experienced perioperative complications which resolved. A statistically significant reduction of generalized tonic-clonic seizures (17 patients; P < 0.05) and complex partial seizures (11 patients; P < 0.05) occurred following ACC. A single patient with atonic seizures became free of atonic seizures. Two patients had a >50% reduction in seizures resulting in falls, a single patient became free of episodes of status epilepticus, and in 2 patients the seizures changed from generalized tonic-clonic seizures to hemiconvulsive seizures. Thus ACC appears to decrease the severity and frequency of disabling seizures in some patients with uncontrolled seizures.

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Anterior callosotomy in the treatment of
Anterior callosotomy in the treatment of medically intractable epilepsies: A study of 43 patients with a mean follow-up of 39 months
✍ Hirokazu Oguni; Dr. AndrΓ© Olivier; Frederick Andermann; Joseph Comair πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 736 KB

We studied the effectiveness of anterior callosotomy in 43 patients whose follow-up period averaged 39 months. These patients had intractable generalized seizures, characterized by a combination of seizure patterns, most frequently drop attacks with generalized tonic-clonic, generalized tonic, and a