## Background Phosphatidylinositol (PI) 3-kinase is activated by a variety of growth factor receptors and the PI 3-kinase/Akt signaling pathway is a key regulator of cell proliferation and survival. The downstream targets of PI 3-kinase/Akt signaling include direct regulators of cell cycle progress
โฆ LIBER โฆ
Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages
โ Scribed by Yukio Fujiwara; Yoshihiro Komohara; Tsuyoshi Ikeda; Motohiro Takeya
- Book ID
- 108586923
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 459 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Phosphatidylinositol 3-kinase signaling
โ
Jolyon Terragni; Julie R Graham; Kenneth W Adams; Michael E Schaffer; John W Tul
๐
Article
๐
2008
๐
BioMed Central
๐
English
โ 541 KB
Nuclear factor-ฮบB and IฮบB kinase are con
โ
Lan Li; Bharat B. Aggarwal; Shishir Shishodia; James Abbruzzese; Razelle Kurzroc
๐
Article
๐
2004
๐
John Wiley and Sons
๐
English
โ 588 KB
Suppression of phorbol-12-myristate-13-a
โ
Yong Pil Hwang; Hyo Jeong Yun; Jae Ho Choi; Keon Wook Kang; Hye Gwang Jeong
๐
Article
๐
2009
๐
John Wiley and Sons
๐
English
โ 490 KB
Matrix metalloproteinase (MMP) plays an important role in the invasion and metastasis of cancer cells. The inhibitory effects of bergamottin, a cytochrome P450 inhibitor from Citrus paradis (grapefruit), on tumor invasion and migration and the possible mechanisms involved in this inhibition were inv