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Coronary constriction by leukotriene C4, D4, and E4 in the intact pig heart

✍ Scribed by David Ezra; Lillie M. Boyd; Giora Feuerstein; Robert E. Goldstein

Book ID
115670820
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
478 KB
Volume
51
Category
Article
ISSN
0002-9149

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Synthesis of the sulfones of leukotriene
Synthesis of the sulfones of leukotriene C4, D4, and E4
✍ Yves Girard; Marie Larue; Thomas R. Jones; Joshua Rokach πŸ“‚ Article πŸ“… 1982 πŸ› Elsevier Science 🌐 French βš– 255 KB

A simple one-step preparation of the sulfones of Leukotriene Cq, D, and E, has been developed by the direct oxidation of the parent compounds. An alternative synthesis of these sulfones has also been carried out by reduction of an acetylenic precursor. Slow reacting substance of anaphylaxis (SRS-A)