Titanocene-catalysed, selective reductio
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Alejandro F. Barrero; Antonio Rosales; Juan M. Cuerva; Andreas Gansäuer; J.Enriq
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Article
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2003
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Elsevier Science
🌐
French
⚖ 198 KB
We report here a novel procedure for the reduction of ketones to secondary alcohols using catalytic quantities of commercially available Cp 2 TiCl 2 , inexpensive Zn dust and water as proton source. Mechanistically the reaction presumably proceeds via titanoxy radicals. In practice this reduction pr