Copy number variations and cancer
β Scribed by Adam Shlien, David Malkin
- Book ID
- 120705413
- Publisher
- BioMed Central
- Year
- 2009
- Tongue
- English
- Weight
- 602 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1756-994X
- DOI
- 10.1186/gm62
No coin nor oath required. For personal study only.
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## Abstract Highβresolution techniques for analysis of genome copy number (CN) enable the analysis of complex cancer somatic genetics. However, the analysis of these data is difficult, and failure to consider a number of issues in depth may result in false leads or unnecessary rejection of true pos
## Abstract We investigated characteristics of germline copy number variations (CNV) in __BRCA1__βassociated ovarian cancer patients by comparing them to CNVs present in sporadic ovarian cancer patients. Germline CNVs in 51 __BRCA1__βassociated, 33 sporadic ovarian cancer patients, and 47 healthy w