Copper(II)-mediated oxidation of 1,2-dioxime to furoxan

✍ Scribed by Oindrila Das; Sayantan Paria; Tapan Kanti Paine

• Book ID: 104095684
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 240 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.07.148

✦ Synopsis

1,2-Dioximes undergo oxidative transformation mediated by copper(II) ions in acetonitrile to form the corresponding furoxans in high yields. A series of 1,2-dioximes including aliphatic, aromatic, and heterocyclic dioximes were oxidized using these mild conditions.