✦ LIBER ✦
Copper(I)-Catalyzed Synthesis of Novel 4-(Trifluoromethyl)-[1,2,3]triazolo[1,5-a]quinoxalines via Cascade Reactions of N-(o-Haloaryl)alkynylimine with Sodium Azide
✍ Scribed by Zixian Chen; Jiangtao Zhu; Haibo Xie; Shan Li; Yongming Wu; Yuefa Gong
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 203 KB
- Volume
- 352
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
Novel tricyclic 4‐(trifluoromethyl)‐[1,2,3]triazolo[1,5‐a]quinoxalines were readily prepared from N‐(o‐haloaryl)alkynylimines and sodium azide via copper(I)‐catalyzed tandem reactions. This synthetic strategy provides an efficient way to access a library of novel heterocyclic compounds that are of interest in drug discovery.