Copper triflate [Cu(OTf)2] is an efficient and mild catalyst for the silylation of α-hydroxyphosphonates to α-trimethylsilyloxyphosphonates with HMDS at room temperature

✍ Scribed by Habib Firouzabadi; Nasser Iranpoor; Sara Sobhani; Soheila Ghassamipour; Zohreh Amoozgar

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 84 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02780-6

✦ Synopsis

A broad, adaptable, high yielding and convenient procedure for the fast conversion of various a-hydroxyphosphonates to a-trimethylsilyloxyphosphonates under mild conditions with HMDS in the presence of a catalytic amount of copper triflate is described. This procedure has also been applied successfully for the silylation of alcohols and phenols.