๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Copper nitrate trihydrate catalyzed efficient synthesis of bis(indolyl)methanes in acetonitrile at room temperature

โœ Scribed by Aayesha Nasreen; Ravi Varala; Srinivas R. Adapa

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
317 KB
Volume
44
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

A catalytic amount of easily available and inexpensive Cu(NO~3~)~3~.3H~2~O (10 mol%) enables electrophilic substitution reaction of indole with structurally divergent aldehydes in acetonitrile to afford the corresponding bis(indolyl)methanes in moderate to excellent yields (65โ€98%) at ambient temperature. The reaction is highly chemoselective and applicable only to aldehydes and not to ketones.

๐Ÿ“œ SIMILAR VOLUMES

Copper Nitrate Trihydrate Catalyzed Effi
Copper Nitrate Trihydrate Catalyzed Efficient Synthesis of Bis(indolyl)methanes in Acetonitrile at Room Temperature.
โœ Aayesha Nasreen; Ravi Varala; Srinivas R. Adapa ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons โš– 19 KB ๐Ÿ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.