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Copper-catalyzed formation of N,N-dimethyl benzamide from nitrile and DMF under an O2 atmosphere

✍ Scribed by Hu, Chenxu; Yan, Xufei; Zhou, Xiangge; Li, Zhengkai


Book ID
121343717
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
286 KB
Volume
11
Category
Article
ISSN
1477-0520

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N,N-dimethylhydrazones of aldehydes can be efficiently oxidized in a catalytic way by hydrogen peroxide associated with methyltrioxorhenium (MTO) as the catalyst to give nitriles. Elimination of dimethylhydroxylamine that is further oxidized to N-methyl-N-methylene N-oxide takes place. This nitrone