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Copper-catalyzed alkyne cycloaddition on electron deficient azides via tetrazolo[1,5-a]pyrimidines

✍ Scribed by Linda I. Nilsson; Anne Ertan; Dirk Weigelt; Jens M. J. Nolsöe


Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
122 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

magnified image Tetrazolo[1,5‐a]pyrimidines are capable of serving as masked azides in copper‐catalyzed Huisgen cyclization with a variety of terminal alkynes, providing a simple protocol for the generation of novel 4′‐substituted 2‐(1′,2′,3′‐triazol‐1′‐yl)pyrimidines. J. Heterocyclic Chem., (2010).


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