Copper-catalysed heteroannulation with alkynes: a general and highly regio- and stereoselective method for the synthesis of (E)-2-(2-arylvinyl) quinazolinones
✍ Scribed by Nitya G Kundu; Gopeswar Chaudhuri
- Book ID
- 108371296
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 175 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## 2-[N-Alkyl(benzyl)-N-(prop-2%-ynyl) ]aminobenzamides 5 reacted with aryl iodides 2 under palladium-copper catalysis to yield disubstituted alkynes 6-13, which underwent a novel cyclisation in the presence of CuI, K 2 CO 3 , n-Bu 4 NBr in acetonitrile to yield (E)-1-alkyl(benzyl)-3-aryl-2-(2-ary
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