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Copolymers of N-isopropylacrylamide can trigger pH sensitivity to stable liposomes

✍ Scribed by Olivier Meyer; Demetrios Papahadjopoulos; Jean-Christophe Leroux


Book ID
117108593
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
89 KB
Volume
421
Category
Article
ISSN
0014-5793

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The aim of this study was to characterize a pH-sensitive liposome formulation bearing a terminally alkylated N-isopropylacrylamide (NIPAM) copolymer with regard to its pH responsiveness, surface properties, and pharmacokinetics. The interacting forces between two lipid bilayers bearing the anchored