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Coordination of TP53 Abnormalities in Breast Cancer: Data from Analysis of TP53 Polymorphisms, Loss of Heterozygosity, Methylation, and Mutations

✍ Scribed by Denisov, Evgeny V.; Sukhanovskaya, Tatiana V.; Dultseva, Tatiana S.; Malinovskaya, Elena A.; Litviakov, Nicolay V.; Slonimskaya, Elena M.; Choinzonov, Evgeny L.; Cherdyntseva, Nadezhda V.


Book ID
121260417
Publisher
Mary Ann Liebert
Year
2011
Tongue
English
Weight
253 KB
Volume
15
Category
Article
ISSN
1945-0265

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TP53 abnormalities have been reported as an early event in the process of cellular transformation of human breast cancers, and involved in mammary-tumor evolution, from in situ to invasive disease. In this study, node-negative (N-) tumors were examined for TP53 allelic loss in relation to different