Coordination chemistry and the carcinogenicity and mutagenicity of chromium(VI)
โ Scribed by Paul O'Brien; Guofang Wang
- Book ID
- 105301207
- Publisher
- Springer Netherlands
- Year
- 1989
- Tongue
- English
- Weight
- 731 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1573-2983
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract In response to the 2005 revised U.S Environmental Protection Agency's (EPA) Cancer Guidelines, a strategy is being developed to include all mutagenicity and other genotoxicity data with additional information to determine whether the initiating step in carcinogenesis is through a mutage
Certain chromium (Cr) compounds are known to be carcinogenic in humans and mutagenic in cell culture. However, the mechanism of Cr mutagenesis is not well understood. It appears that intracellular reduction of Cr by agents such as glutathione plays a role in the induction of DNA damage. We have used