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Coordinated regulation of ceruloplasmin and metallothionein mRNA by interleukin-1 and copper in HepG2 cells

✍ Scribed by Angela A.I Daffada; Stephen P Young

Book ID
117111299
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
121 KB
Volume
457
Category
Article
ISSN
0014-5793

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Amplification of the metallothionein-1 a
Amplification of the metallothionein-1 and metallothionein-2 genes in copper-resistant hepatoma cells
✍ Mark J. Czaja; Francis R. Weiner; Jonathan H. Freedman πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 623 KB

The molecular basis for increased metallothionein concentrations in copperresistant hepatoma cells was examined. The copper-resistant cell line HAC, , , , which is maintained in 600 k m copper, had increased steady-state mRNA levels for both the metallothionein-1 (MT-1) and the metallothionein-2 (MT