Coordinated control of renal Ca2+ transport proteins by parathyroid hormone
✍ Scribed by VAN ABEL, MONIQUE; HOENDEROP, JOOST G J; VAN DER KEMP, ANNEMIETE W C M; FRIEDLAENDER, MICHAEL M; VAN LEEUWEN, JOHANNES P T M; BINDELS, RENÉ J M
- Book ID
- 109067380
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 282 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0085-2538
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## Abstract As part of its catabolic action in bone, parathyroid hormone (PTH) inhibits extracellular matrix mineralization. We previously showed that PTH dose‐dependently induces matrix gla protein (MGP) expression in osteoblasts and this induction is at least partially responsible for PTH‐mediate
To characterize the Ca2+ transport process across the apical membrane of the rabbit connecting tubule (CNT), we examined the effects of luminal pressure on parathyroid hormone (PTH)-dependent apical Ca2+ transport in this segment perfused in vitro. An increase of perfusion pressure (0.2 to 1.2 KPa)