## Abstract Plateletβderived growth factor (PDGF) and plateletβpoor plasma, which lacks PDGF, both induce a rapid increase in the rate of total protein synthesis within quiescent, densityβarrested Balb/cβ3T3 cells. This stimulation of protein synthesis is associated with an increased aggregation of
Coordinate Control of 3T3 cell Proliferation by Platelet-Derived Growth Factor and Plasma Components
β Scribed by Arthur Vogel, Elaine Raines, Beverly Kariya, Mary-Jane Rivest and Russell Ross
- Book ID
- 123655187
- Publisher
- National Academy of Sciences
- Year
- 1978
- Tongue
- English
- Weight
- 769 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/68333
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To examine the role of platelet-derived growth factor (PDGF) in the in vivo regulation of Schwann cell proliferation, steady-state levels of mRNAs encoding PDGF A and B chains, and PDGF a and p receptors were measured in immature and adult rat sciatic nerves and in cultured rat Schwann cells. PDGF B