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Cooperative tumorigenic effects of germline mutations in Rb and p53

✍ Scribed by Williams, Bart O.; Remington, Lee; Albert, Daniel M.; Mukai, Shizuo; Bronson, Roderick T.; Jacks, Tyler


Book ID
109916668
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
695 KB
Volume
7
Category
Article
ISSN
1061-4036

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Identification of RB and p53 mutations i
✍ Akira Murakami; Harutaka Tanaka πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

We analyzed the genomic structure and mRNA of the RB and p53 genes in four mouse lymphoid leukemia cell lines (DL-1, DL-5, DL-8, and DL-12). Although no gross structural alteration of the RB gene was observed in any cell line, abnormalities of RB mRNA were detected in at least two cell lines. RB mRN