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Cooperative role of telomerase activity and p16 expression in the prognosis of non-small cell lung cancer

✍ Scribed by P. Iniesta; R. Gonzalez-Quevedo; A. Moran; C. De Juan; A. Sanchez-Pernaute; A. Torres; E. Díaz-Rubio; J.L. Balibrea; M. Benito

Book ID
117658026
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
340 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Abstract The cyclin‐dependent kinase inhibitor known as __p16__ (__CDK41, CDKN2, INK4A, MTS1__) has been proposed as a tumor suppressor gene on chromosome segment 9p21. We have evaluated __CDKN2__ alterations in 34 non‐small cell lung cancers (NSCLCs) with matched normal tissue controls and in 9