✦ LIBER ✦

Cooperative binding of n-mers with steric hindrance to finite and infinite one-dimensional lattices

✍ Scribed by Takashi Tsuchiya; Attila Szabo

Publisher: Wiley (John Wiley & Sons)
Year: 1982
Tongue: English
Weight: 686 KB
Volume: 21
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360210510

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✦ Synopsis

Abstract

The cooperative binding of n‐mers to a finite ring, a finite open chain, and an infinite chain is treated in a unified way using the matrix method. For an infinite chain, the implicit closed‐form expression (“Scatchard formula”) for the fraction of bound sites obtained by McGhee and von Hippel, is simply rederived using a procedure involving implicit differentiation of the characteristic equation. A variety of models for n‐mer binding that incorporate steric hindrance for formulated, and corresponding Scatchard formulas are derived using our procedure.

📜 SIMILAR VOLUMES

A general secular equation for cooperati

A general secular equation for cooperative binding of n-mer ligands to a one-dimensional lattice

✍ Yi-Der Chen 📂 Article 📅 1990 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 680 KB

## Abstract The binding of __n__‐mer ligands to a one‐dimensional lattice involving many ligand species and complex multiple‐binding mechanisms is studied. We show that, when derived using the sequence‐generating function method of Lifson, the secular equation of any binding system with a finite nu