Hydrogen-bonding interactions in the act
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Cristobal Alhambra; Jiali Gao
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Article
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2000
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John Wiley and Sons
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English
β 260 KB
π 2 views
Molecular dynamics simulation of the Michaelis complex, phospho-enzyme intermediate, and the wild-type and C12S mutant have been carried out to examine hydrogen-bonding interactions in the active site of the bovine low molecular weight protein-tyrosine phosphatase (BPTP). It was found that the S Ξ³ a