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Convulsant action of diphenyl diselenide in rat pups: measurement and correlation with plasma, liver and brain levels of compound

✍ Scribed by Marina Prigol; Simone Pinton; Ricardo Schumacher; Cristina Wayne Nogueira; Gilson Zeni

Book ID
105870853
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
287 KB
Volume
84
Category
Article
ISSN
0340-5761

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## Abstract D, L‐3‐hydroxy‐3‐ethyl‐3‐phenylpropanamide (HEPP) is a synthetic drug with anticovulsant effects in a variety of seizure models. HEPP pharmacokinetics was studied after single 50 mg kg^βˆ’1^ intravenous (IV), intraperitoneal (IP), and oral (PO) administration in male albino Wistar rats. T