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Conversion of the cholesterol sidechain to a 17-acetyl group by remote chlorination reactions

✍ Scribed by Uday Maitra; Ronald Breslow

Publisher: Elsevier Science
Year: 1986
Tongue: French
Weight: 203 KB
Volume: 27
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)84722-x

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✦ Synopsis

Two methods to convert cholesterol to pregnane derivatives are described. In one, template directed chlorination of C-20 with an iodoaryl ester attached at the 6 p position was used to convert i-cholesterol to pregnenolone.

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