𝔖 Bobbio Scriptorium
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Conversion of protected serine and threonine to corresponding dehydroamino acids under mild conditions

✍ Scribed by Hanna Wojciechowska; Roman Pawłowicz; Ryazard Andruszkiewicz; Jolanta Grzybowska

Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
153 KB
Volume
19
Category
Article
ISSN
0040-4039

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✦ Synopsis

Dobydroamiao acids are important constituents of oertain psptidr antibiotics l/ . Recently, the synthesis of dohydroalaaine and 2-aoylamiaocrotonate derivatives uas doscrib.d2! ~erine sad tbreoalne drrivativrs have boen convertad by ohloriaation reactioa with phosphorus peatachloride and subsequent elimination, using a tertiary amino ss a basr to oorresponding dehydroalanines and 2-acvlamioocrotonates respectively.

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