Conversion of palmitate to unsaturated fatty acids differs in aNeurospora crassamutant with impaired fatty acid synthase activity

Prolonged exposure to palmitate impairs

Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells

✍ A.S. Pimenta; M.P. Gaidhu; S. Habib; M. So; S. Fediuc; M. Mirpourian; M. Musheev 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

## Abstract The aim of this study was to investigate the chronic effects of palmitate on fatty acid (FA) oxidation, AMPK/ACC phosphorylation/activation, intracellular lipid accumulation, and the molecular mechanisms involved in these processes in skeletal muscle cells. Exposure of L6 myotubes for 8