Conversion of Human Umbilical Cord Mesenchymal Stem Cells in Wharton's Jelly to Dopaminergic Neurons In Vitro: Potential Therapeutic Application for Parkinsonism
β Scribed by Yu-Show Fu; Yun-Chih Cheng; Maan-Yuh Anya Lin; Henrich Cheng; Pei-Ming Chu; Shih-Chich Chou; Yang-Hsin Shih; Miau-Hwa Ko; Min-Shan Sung
- Book ID
- 111843550
- Publisher
- AlphaMed Press
- Year
- 2006
- Tongue
- English
- Weight
- 476 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1066-5099
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## Abstract Recent studies have demonstrated that mesenchymal stem cells could differentiate into germ cells under appropriate conditions. We sought to determine whether human umbilical cord Wharton's jellyβderived mesenchymal stem cells (HUMSCs) could form germ cells in vitro. HUMSCs were induced
We investigated the effect of human umbilical mesenchymal stem cells (HUMSCs) from Wharton's jelly on carbon tetrachloride (CCl 4 )-induced liver fibrosis in rats. Rats were treated with CCl 4 for 4 weeks, and this was followed by a direct injection of HUMSCs into their livers. After 4 more weeks of