Conversion of Homocysteine to Methionine by Methionine Synthase: A Density Functional Study
โ Scribed by Jensen, Kasper P.; Ryde, Ulf
- Book ID
- 127290117
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 77 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The cblE type of homocystinuria is a rare autosomal recessive disorder caused by impaired reductive activation of methionine synthase. Although earlier biochemical studies proposed that the methionine synthase enzyme might be activated by two different reducing systems, mutations were reported in on
Functional methionine synthase deficiency due to abnormal methylcobalamin metabolism causes megaloblastic anemia, moderate to severe developmental delay, lethargy, and anorexia in association with homocystinuria. Patients with this disorder of cobalamin metabolism can be classified into two separate