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Conversion of Alcohols to Protected Guanidines Using the Mitsunobu Protocol

✍ Scribed by Dharmpal S. Dodd; Alan P. Kozikowski

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 246 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79943-6

No coin nor oath required. For personal study only.

✦ Synopsis

An eficient method for the direct conversion of alcohols to guanidines is presented A variety of alcohols react with I and 2 under Mitsunobu conditions to give the corresponding guanidines in high

yield.

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