Conversion of alcohols into alkyl bromides and iodides via O-alkylisoureas

✍ Scribed by Stephen P. Collingwood; Alan P. Davies; Bernard T. Golding

• Publisher: Elsevier Science
• Year: 1987
• Tongue: French
• Weight: 225 KB
• Volume: 28
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)96534-1

✦ Synopsis

Treatment of 0-alkylisoureas with trifluoromethanesulphonic acid and a tetrabutylammonium salf (bromide or iodide) affords alkyl halides in high yields. '+?'I 7 f CH,CXCH, b CsH, ,CH(CH,) S CHaCzCCaH, c =-CsH, t h CHaCHgCHCHaCHECHCH, d CsHsCH, i CH3CH&HCH+CCH, e CH,CHECHCH, j CH,=CHCH,C(CH3),CH,