Conversion of 5-hydroxy to 5-amino and 5-alkoxypyrazolidines
β Scribed by L. A. Sviridova; S. V. Afanas'eva; K. N. Zelenin; G. A. Golubeva; I. P. Bezhan; Yu. G. Bundel'
- Book ID
- 112369305
- Publisher
- Springer US
- Year
- 1987
- Tongue
- English
- Weight
- 329 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0009-3122
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## Abstract The application of the βdirect amide cyclizationβ conditions to the linear __Ξ΄__βhydroxy diamide **11** is described (__Schemeβ 3__). Instead of the cyclization to the expected nineβmembered cyclodepsipeptide, only the chloro acid **12** was obtained. Its formation could be explained by
An enzymatic method has been developed to synthesize S-methyldeoxycytidine triphosphate (m'dCTP) starting with dCMP and formaldehyde as substrates. Methylation is catalyzed by a dCMP methyltransferase in the presence of tetrahydrofolic acid. The resulting m'dCMP is converted to m'dCTP by a kinase pr