Conversion of 3-Hydroxyanthranilic Acid to Quinolinic Acid in Presence of Rat Liver treated with 2-Acetylaminofluorene
โ Scribed by QUAGLIARIELLO, E.; AURICCHIO, S.; RINALDI, E.
- Book ID
- 109597795
- Publisher
- Nature Publishing Group
- Year
- 1958
- Tongue
- English
- Weight
- 121 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/181624a0
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## Abstract In order to cast light on carcinogenโspecific molecular mechanisms underlying experimental hepatocarcinogenesis in rats, in vivo mutagenicity and mutation spectra of known genotoxic rat hepatocarcinogens __N__โnitrosopyrrolidine (NPYR), and 2โaminoโ3โmethylimidazo[4,5โ__f__]quinoline (I
The dehydration of aldoximes with 2-methyleneol,3-dioxepane (MDO) proceeds smoothly in the presence of a catalytic amount of Lewis acid such as scandium(Ill) triflate to give corresponding nitriles in moderate to high yields under mild conditions.