Conversion of 2-Alkyl-2-(2-oxopropyl)cyclopentane-1,3-diones into 2,3,5- and 2,3,4-Trisubstituted Cyclopent-2-enones by Intramolecular Aldolizations to 2,3-Diacylcyclopropanolates Followed by Remarkable Skeletal Rearrangements 1
✍ Scribed by Schick, Hans; Roatsch, Birgit; Schramm, Siegfried; Gilsing, Hans-Detlev; Ramm, Matthias; Gründemann, Egon
- Book ID
- 120469111
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 196 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract In contrast to earlier reported unsuccessful experiments the Michael addition of prop‐2‐enal to 2‐methylcyclopentane‐1,3‐dione (1) affords 3‐(1‐methyl‐2,5‐dioxocyclopentyl)propanal (3) in 90% yield, if the reaction is carried out in water without a basic catalyst. This aldehyde is conve
## Abstract New 4‐aryl‐2,3‐dihydro‐2‐styryl‐1,5‐benzothiazepines **8–13** have been synthesized by an acid catalyzed reaction of 2‐arninothiophenol (**1**) and (__E,E__)‐cinnamylideneacetophenones **2–7.** Ring contraction of 1,5‐benzothiazepines **8–13** provided 2,2‐disubstituted 3‐acetyl‐2,3‐dih