Conversion of 14C-labeled eicosapentaenoic acid (n-3) to leukotriene C5
✍ Scribed by Sven Hammarström
- Book ID
- 115738248
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 207 KB
- Volume
- 663
- Category
- Article
- ISSN
- 0005-2760
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📜 SIMILAR VOLUMES
Two lqC-labelled leukotriene receptor antagonists were prepared from two aryl bromides and potassium [ 14C]cyanide. cyanide was converted to copper(1) [L4C]cyanide and was subsequently used to displace the bromine atom from two dry1 bromides, 2-dodecylbromobenzene and 2-(8-phenyloctyl)bromobenzene.
## Abstract The synthesis of indole‐3‐acetyl‐2‐^14^C‐N‐aspartic acid from carrier‐free indole‐3‐acetic acid‐2‐^14^C (54.5 mCi/mmole) and bis‐t‐butyl‐l‐aspartic acid was accomplished by coupling with dicyclohexylcarbodiimide followed by removal of the ester blocking groups by treatment with 2 N NaOH