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Converging evidence for a cognitive anomaly in early psychopathology

✍ Scribed by Leyan O.L. Fernandes; Jennifer Keller; Janine E. Giese-Davis; Blair D. Hicks; Daniel N. Klein; Gregory A. Miller

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 220 KB
Volume: 36
Category: Article
ISSN: 0048-5772
DOI: 10.1017/s0048577299951727

No coin nor oath required. For personal study only.

✦ Synopsis

Subcomponents of the N200 component of the event‐related brain potential believed to be differentially sensitive to involuntary and voluntary cognitive processes were examined. Nonpatients (N= 131) identified initially by the Chapman and Depue research scales and classified later on the basis of diagnostic symptom clusters and family psychiatric history provided converging evidence for an intact mismatch negativity subcomponent. In contrast, the N2b subcomponent distinguished several groups of subjects. Results suggested abnormal voluntary cognitive processing, perhaps reflecting compensatory efforts in subjects at risk for or manifesting psychopathology, particularly those showing negative symptoms.

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