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Convergent stereospecific synthesis of LL-Z1640-2 (or C292), hypothemycin and related macrolides. Part 2

✍ Scribed by Patrice Sellès; Robert Lett


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
162 KB
Volume
43
Category
Article
ISSN
0040-4039

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Convergent stereospecific synthesis of C
✍ Patrice Sellès; Robert Lett 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 330 KB

The stereospecific synthesis of the precursors required for the 14-membered ring formation either via an intramolecular Suzuki coupling or via an intermolecular Suzuki coupling followed by a macrolactonisation is herein reported. One-pot Suzuki couplings were here achieved with vinyldisiamylboranes