Convergent Functional Genomics of bipolar disorder: From animal model pharmacogenomics to human genetics and biomarkers

Gene expression analysis of peripheral b

Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches

✍ Frank A. Middleton; Carlos N. Pato; Karen L. Gentile; Lindsay McGann; Andrea M. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 1 views

We performed global RNA transcript analysis and comprehensive gene group analysis of peripheral blood leukocyte (PBL) RNA from two groups of matched sib-pairs that were discordant for either schizophrenia (n = 33 sib-pairs) or bipolar disorder (n = 5 sib-pairs). The pairs chosen for these analyses w