Conventional protein kinase C and atypical protein kinase Cζ differentially regulate macrophage production of tumour necrosis factor-α and interleukin-10
✍ Scribed by Andrew D. Foey; Fionula M. Brennan
- Book ID
- 108781424
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 325 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0019-2805
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Atypical protein kinase Cs zeta and lambda/iota play a functional role in the regulation of NGF‐induced differentiation and survival of pheochromocytoma, PC12 cells [Coleman and Wooten, 1994; Wooten et al., 1999]. Here we demonstrate an NGF‐dependent interaction of aPKC with its binding
## Abstract The proinflammatory cytokine tumor necrosis factor (TNF) α is mainly produced in cells from the monocyte/macrophage lineage. TNFα is also a key signaling molecule in the liver functioning as an important physiological and pathogenic mediator. In hepatocytes or human hepatoma cells TNFα
The early growth response-1 (Egr-1) gene has been identified as a nuclear transcriptional factor and implicated in the regulation of growth and differentiation of osteoblastic cells. In the present study, we investigated whether Egr-1 mRNA is expressed and induced by interleukin-1 beta, (IL-beta) an