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Conventional and sustained-release valproate in children with newly diagnosed epilepsy: a randomized and crossover study comparing clinical effects, patient preference and pharmacokinetics

✍ Scribed by José L. Herranz; Rosa Arteaga; Javier Adín; Juan A. Armijo

Publisher
Springer
Year
2006
Tongue
English
Weight
186 KB
Volume
62
Category
Article
ISSN
0031-6970

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Conventional and controlled release valp
Conventional and controlled release valproate in children with epilepsy: a cross-over study comparing plasma levels and cognitive performances
✍ O.F. Brouwer; M.S.M. Pieters; P.M. Edelbroek; A.M. Bakker; A.A.C.M. van Geel; Th 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 962 KB

We studied plasma levels and behavioural effects of a newly developed controlled release formulation of valproate (VPA-CR) in children with epilepsy. Valproate plasma levels and performances in attention and vigilance tasks were monitored during a 12-h period (daytime), both during monotherapy of co