Convenient synthesis of functionalized terphenyls
β Scribed by A.A. Greenfield; J.A. Butera; C.E. Caufield
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 126 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
A convenient synthetic methodology amenable for rapid synthesis of differentially functionalized terphenyls is described. Orthogonality requirements for the incorporation of phenoxy acetic acid and carboxamide function have been satisfied by utilization of hydroxyethoxy group as a precursor of the acid. Highly efficient and universal procedures have been developed for acid and amide formation.
π SIMILAR VOLUMES
Functionalized vinylepoxides were synthesized, in high yields, from tx-bromoaldehydes and -ketones via vinylalumination, followed by cyclization with K2CO3 or KF under non-aqueous conditions.
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