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Convenient synthesis of bis(indolyl)alkanes and bis(pyrrolyl)alkanes by Cu(OTf)2-catalyzed addition of indole and pyrrole to acetylenic sulfone

✍ Scribed by Mei-Hua Xie; Fa-Dong Xie; Gao-Feng Lin; Jin-Hua Zhang

Book ID: 104097292
Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 287 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.12.093

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✦ Synopsis

Sulfonyl-containing bis(indolyl)alkanes and bis(pyrrolyl)alkanes were synthesized conveniently by Cu(OTf) 2 -catalyzed double Michael addition of indole and pyrrole to acetylenic sulfone.

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