Synthesis of 4-13C-4-hydroperoxycyclopho
β
Chorng-Kei Ho; Susan M. Ludeman
π
Article
π
1990
π
John Wiley and Sons
π
French
β 468 KB
π 1 views
## Abstract New synthetic routes were developed for incorporating ^13^C into the oxazaphosphorine ring and nitrogen mustard functionality of cyclophosphamide metabolites. 1,2β^13^C~2~βVinylbromide and ethylene oxide were used to synthesize 3,4β^13^C~2~β3βbutenyl N,Nβbis(2βchloroethyl)phosphorodiami