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Convenient syntheses of some α-deuterated alkyl mesityl ketones by exchange reactions

✍ Scribed by A. G. Pinkus; A. Sabesan; Ravi Subramanyam


Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
212 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

Three alkyl mesityl ketones (methyl, ethyl, and isopropyl) deuterated in the α‐positions were prepared in good yields (82‐89%) by exchange with deuterium oxide using dioxane solvent and various catalysts. Little or no exchange was obtained when reactions were attempted under conditions used in published procedures for other ketones. Infrared and ^1^H nmr spectral evidence in support of structural assignments of deuterated ketones is given.