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Convenient syntheses of adenosine 5′-diphosphate, adenosine 5′-methylenediphosphonate, and adenosine 5′-triphosphate

✍ Scribed by Vyas M. Dixit; C.Dale Poulter


Book ID
104241399
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
201 KB
Volume
25
Category
Article
ISSN
0040-4039

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✦ Synopsis


AbhXh_ac.C Adenosine 5'-tosylate is converted to adenosine 5'-diphosphate (ADPI, adenosine 5'- methylenediphosphonate, and adenosine 5'-triphosphate (ATP) in good yields by direct displacement with the appropriate inorganic salt.

Nucleosides are normally phosphorylated by displacement at an activated phosphorus with a nucleophilic sugar hydroxyl.1-5


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