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Convenient syntheses of (3S,5S)-carbapenam-3-carboxylates and their biosynthetic relevance

✍ Scribed by Barrie W Bycroft; Siri Ram Chhabra; Barrie Kellam; Paul Smith

Book ID: 104252812
Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 117 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02731-4

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✦ Synopsis

Starting from readily available glutamate derivatives, facile stereoselective syntheses of (3S,5S)-carbapenam-3-carboxylates have been developed. Their significance in confirming the absolute configuration of the natural material is discussed.

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