Convenient One-Pot Synthesis of Chromone Derivatives and Their Antifungal and Antibacterial Evaluation
β Scribed by Abdel Ghani, Sherif B.; Mugisha, Patrick J.; Wilcox, Juliet C.; Gado, Emad A. M.; Medu, Erere O.; Lamb, Andrew J.; Brown, Richard C. D.
- Book ID
- 119996702
- Publisher
- Taylor and Francis Group
- Year
- 2013
- Tongue
- English
- Weight
- 258 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0039-7911
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One-pot four-component reactions of aromatic aldehyde, Meldrum's acid, ethyl-4,4,4-trifluoro-1,3dioxobutanoate, and ammonium acetate afford ethyl 2-hydroxy-6-oxo-4-aryl-2-(trifluoromethyl)piperidine-3-carboxylate in good yields. The one-pot four-component process consists of an initial Michael addit
## Abstract For Abstract see ChemInform Abstract in Full Text.