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Convenient genotyping of six myostatin mutations causing double-muscling in cattle using a multiplex oligonucleotide ligation assay

✍ Scribed by L Karim; W Coppieters; L Grobet; M Georges; A Valentini


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
187 KB
Volume
31
Category
Article
ISSN
0268-9146

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✦ Synopsis


We herein describe a procedure that allows for simultaneous genotyping of six loss‐of‐function mutations in the bovine myostatin gene associated with the double‐muscling phenotype. The proposed method relies on a multiplex oligonucleotide ligation assay and detection of the fluorescently labelled products using automatic sequencers.