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Convenient access to two enantiomeric oxirane synthons bearing a quaternary gem-dimethyl carbon center: Synthesis of 3S-(+) and 3R-(−)-2,2-dimethyl-3,4-oxo-1-butanol from R-(−)-pantolactone

✍ Scribed by Pierre Lavallée; Réjean Ruel; Louis Grenier; Martine Bissonnette


Book ID
104218185
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
220 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis


Starting with the commercially available R(-)-Pantolactone and using three different pathways, the synthesis of two new and potentially use ful enantiomeric hydroxy epoxide s ynthons possess ing a quat ernary gem-dimethyl carbon center is r eport ed.