Controlling the Type I error rate by using the nonparametric bootstrap when comparing means

Inflated type I error rates when using a

Inflated type I error rates when using aggregation methods to analyze rare variants in the 1000 Genomes Project exon sequencing data in unrelated individuals: summary results from Group 7 at Genetic Analysis Workshop 17

✍ Nathan Tintle; Hugues Aschard; Inchi Hu; Nora Nock; Haitian Wang; Elizabeth Pugh 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB 👁 2 views

## Abstract As part of Genetic Analysis Workshop 17 (GAW17), our group considered the application of novel and standard approaches to the analysis of genotype‐phenotype association in next‐generation sequencing data. Our group identified a major issue in the analysis of the GAW17 next‐generation se